Elf Score Calculator. Nov 7, 2025 · Learn how the FIB-4 Index uses AST, ALT, platelets,
Nov 7, 2025 · Learn how the FIB-4 Index uses AST, ALT, platelets, and age to estimate liver fibrosis risk—plus how to self-calculate without charges. FIB-4 Calculator for NAFLD NB This is only valid for non-alcoholic fatty liver disease (NAFLD) and is intended for use in conjunction with the NCL Abnormal LFT pathway. Aug 1, 2018 · The reference range of the ELF score overlap with the area defined as moderate fibrosis by the manufacturer. Use The Enhanced Liver Fibrosis (ELF™) blood test is a simple, accurate, non-invasive test that provides a simple, unitless numeric score that is generated via an algorithm for use in advanced liver fibrosis. Enhanced Liver Fibrosis (ELF) Score - The Enhanced Liver Fibrosis (ELF) score predicts progression to cirrhosis and liver-related events in patients with advanced fibrosis due to NASH. High biological variation of HA was diminished by the natural logarithm in the calculation of the ELF score. You can find the result interpretation and guidelines on the original study that published the score below the form. ELF Score ≥10. If you are at risk of liver disease a FIB-4 or ELF test can help find out how much scarring is in your liver and what should happen next. What analytes are used to calculate the ELF score? Question 3. Use the interactive slide rule to see how the ELF score can indicate the state of liver fibrosis. Is the ELF test included in any guidelines? References Enhanced Liver Fibrosis (ELF™). 51 suggests advanced liver fibrosis and is an indication for referral to Hepatology clinic. We would like to show you a description here but the site won’t allow us. The ELF Test is a non-invasive blood test that measures three direct markers of fibrosis: hyaluronic acid (HA), procollagen III amino-terminal peptide (PIIINP), and tissue inhibitor of matrix metalloproteinase 1 (TIMP-1). Reference values and influence factors for the ELF score Estimates amount of scarring in the liver based on several laboratory tests. There are several liver conditions that are defined under this term which includes steatosis which is or not accompanied by various degrees of inflammation and cannot be appointed to alcohol co Calculate your risk of liver fibrosis based on your age, height, weight, and laboratory test results. Sep 22, 2023 · Question 1. 394 × ln (TIMP-1). The ELF Score is recommended by AACE guidelines,6 as its measurements have proven valuable for identifying patients with advanced fibrosis (F3 or F4) at risk of progressing to cirrhosis and liver-related events. It will appear in the oval on the far right (highlighted in yellow). How do I interpret ELF score results? Question 4. However, both modalities help prioritise patients for biopsy and can be complementary. FIB-4 Index What it measures: fibrosis Who should take it: anyone concerned about their liver Where to get it: primary care provider, online calculator The FIB-4 Index is a blood-based diagnostic test that looks at underlying fibrosis that can be used as a measure to help determine NAFLD/NASH status. The ELF score has been assessed in a number of studies and has shown comparable accuracy with the Fibroscan. 751 × ln (PIIINP) + 0. The NAFLD fibrosis score is a noninvasive system that uses AST, ALT, platelet count, and albumin levels. The accuracy of results can be impacted by extremely elevated BMI. 851 × ln (HA) + 0. 278 + 0. The use of the ELF score has suitable analytical and acceptable biological performance characteristics for clinical practice. Aug 1, 2013 · The ELF score was measured in 400 healthy controls and 79 chronic hepatitis C patients using an ADVIA Centaur automated system. 51, then advanced liver fibrosis is unlikely. Check your ELF Score Liver Calculator results to assess liver fibrosis, track liver health, and understand your risk with accurate scoring. The Enhanced Liver Fibrosis (ELF) Score is a noninvasive test that indicates whether a patient with NASH and advanced fibrosis has a higher or lower risk of disease progression to cirrhosis (for those with F3 fibrosis) or other liver-related clinical events (for those with F3 or F4 fibrosis) within 1 to 4 years. Estimates amount of scarring in the liver based on several laboratory tests. noninvasive blood test requiring a single nonfasting tube of serum, the ELF Score is based on 3 direct markers of fibrosis: We would like to show you a description here but the site won’t allow us. If the ELF Score is <10. Estimates amount of scarring in the liver based on several laboratory tests. However, there is a need for independent validation of the ELF score with regard to validated reference values, influencing factors and suitable cut-off values. An ELF Score ≥10. 7–10 ELF is included as a The Enhanced Liver Fibrosis (ELF) Score is a noninvasive test that indicates whether a patient with NASH and advanced fibrosis has a higher or lower risk of disease progression to cirrhosis (for those with F3 fibrosis) or other liver-related clinical events (for those with F3 or F4 fibrosis) within 1 to 4 years. Please fill out required fields. The ELF score was calculated using the published algorithm combining TIMP-1, PIIINP and HA values. ROC analyses were performed to study marker validity. While originally developed to detect liver fibrosis among patients with Hepatitis C and HIV Jan 23, 2023 · The ELF score is not for use in the diagnosis of NASH, the staging of fibrosis, the serial monitoring of disease progression, or the monitoring of effects of therapeutic products. Nov 11, 2025 · The ELF score is calculated using an automated logarithmic algorithm that combines three serum markers of extracellular matrix metabolism: hyaluronic acid (H As per the locally agreed primary care pathway, the ELF test should be considered for the assessment of liver fibrosis in adult patients with NAFLD. What is the FDA indication for the ELF test? Question 2. Sample type: serum sample Turn-around time: within 2 weeks Aug 1, 2018 · The reference range of the ELF score overlap with the area defined as moderate fibrosis by the manufacturer. Assess your liver fibrosis risk with the eLIFT Score Calculator—a user-friendly, non-invasive tool for quick, reliable screening and prompt action today. The ELF Score can help identify patients with advanced fibrosis (F3 or F4) at risk of progressing to cirrhosis and liver-related events (LREs). If ELF Score <10. . Fibrosis-4 (FIB-4) Calculator Share The Fibrosis-4 score helps to estimate the amount of scarring in the liver. Siemens Healthcare Diagnostics Inc; 2022. Enter the required values to calculate the FIB-4 value. The ELF score is computed using the following formula: The ELF score = 2. The ELF test is a panel of three biomarkers: type III procollagen peptide (PIIINP), hyaluronic acid (HA), and tissue inhibitor of metalloproteinase-1 (TIMP1). Both the ELF score and Fibroscan can better predict a patient’s long-term survival than a biopsy alone. 51 then retest in 3 years (repeat requests made within this time frame will be rejected by the clinical biochemistry laboratory). If your patient is morbidly obese, consider using a fibrosis score that does not incorporate BMI, such as FIB4. The NAFLD fibrosis score calculator identifies liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). Furthermore, the FIB-4 index is another noninvasive marker for liver fibrosis, and its usefulness has been documented [19, 20]. The ELF Score is the first noninvasive biomarker blood test for prognostic risk assessment in advanced MASH. Nov 17, 2022 · ELF score defines a three-marker fibrosis test (TIMP-1, PIIINP, HA) for assessing advanced fibrosis in NAFLD, guiding referrals and monitoring intervals. Sullivan Nicolaides Pathology has recently introduced a new panel of the most promising direct markers, which are incorporated into a calculation, the Enhanced Liver Fibrosis score (ELF score). Clinical Indications Enhanced Liver Fibrosis (ELF) Score - The Enhanced Liver Fibrosis (ELF) score predicts progression to cirrhosis and liver-related events in patients with advanced fibrosis due to NASH. Package insert. Patients’ fibrosis stage was defined histologically. Aug 1, 2013 · The ELF score consisting of single markers of hepatic matrix metabolism is one of the first commercially available serum multimarker fibrosis tests. How the ELF Score is calculated This NAFLD fibrosis score calculator stratifies the degree of fibrosis to the liver in nonalcoholic fatty liver disease patients by assigning a specific stage. In conjunction with other laboratory findings and clinical assessments, an ELF Score can aid the diagnosis and assessment of the severity of liver fibrosis in patients with chronic liver disease. The ELF score is derived from an algorithm that combines measurements of PIIINP, TIMP-1, and HA. The ELF Score can be used as a prognostic marker for patients who need urgent specialized intervention. 51 suggests advanced liver fibrosis and is an indication for referral to a specialist in hepatology. These values are summarized into a single score, which can be compared to different thresholds for diagnosis. 7–10 ELF is included as a Nov 8, 2025 · Wondering how do you calculate your ELF score? This guide explains the lab-based process for the Enhanced Liver Fibrosis test, detailing what it measures and how doctors interpret the results to assess liver health and prognosis. How the ELF Score is calculated This is a health tool that assesses the level of fibrosis, scarring of the liver, consistent with the existence of nonalcoholic fatty liver disease (NAFLD).